Electrochemotherapy (ECT) is combination treatment of short electric pulses and chemotherapy, which both are administrated through local or intravenous treatment. The ECT therapy makes it possible to deliver drugs to the cell interior. The short, intense electric pulses make the cell membrane transiently permeable, allowing the chemotherapeutic to reach the cell interior. The treatment can be used for cutaneous as well as subcutaneous tumours. Electrochemotherapy has been used to treat patients clinically with drugs such as bleomycin and cisplatin since the beginning of the 1990’s. Electrochemotherapy is used in many countries around the world, and to date more than 4,000 patients have been treated. The latest development within ECT has also shown that there is a possibility, by using surgical procedures, to also treat internal tumours.
ChemoTech and electrochemotherapy
ChemoTech’s founders have long experience of research and clinical development of electrochemotherapy. A wide range of tumours, such as different types of melanoma, primary and metastasised breast cancer as well as head- and neck cancer have been treated by ChemoTech’s founders. The knowledge gained from the vast clinical experience has laid the foundation to ChemoTech.
ECT Generation II & III
Through technical innovations, ChemoTech aims to develop new solutions, which allow for new applications of ECT, including the treatment of cancer in internal organs, especially in prostate gland. Today, we have patents pending for what we call ECT generation II and ECT generation III.
When it comes to prostate cancer, we will use a unique, minimally invasive method and ultrasound guidance to reach the prostate gland with two to four electrodes to make it susceptible to local chemotherapy. The great benefit is that we can kill cancer cells without affecting potency, continence or fertility. Since ECT already is an approved treatment, our aim is to start clinical studies in the near future. Our long-term ambition is to establish a treatment method that can be used to treat a wide range of different cancer cells.
Clinical studies have shown that ECT has a good therapeutic effect on a number different types of cancer tumours. There are today a large number of studies to support this claim. Particularly interesting is the effects of ECT treatment on tumours that previously has not responded to traditional chemotherapy.